Sionna Therapeutics, Inc. Insider Trading Activity
Every SEC Form 4 insider transaction reported for Sionna Therapeutics, Inc. (SION), sourced directly from SEC EDGAR and updated as new filings are accepted.
By Trabud · Insider-trading data from SEC EDGAR
Latest filing:
Compiled automatically from SEC EDGAR Form 4 filings and refreshed daily. Figures count purchases (code P) and sales (code S) only — not grants, option exercises, or gifts. How this page is built. Not investment advice.
Quick Answer
Are SION insiders buying or selling?
In the last 12 months, Sionna Therapeutics, Inc. insiders reported 0 open-market purchases ($0) and 33 sales ($184.0M) — net selling of $184.0M. Since February 2025, Trabud has recorded 48 Form 4 filings for SION: 7 buys ($63.4M) and 41 sells ($190.5M).
Source: SEC EDGAR Form 4
Key Statistics (February 2025 – Sep 21, 2026)
Total Form 4 filings
48
SEC EDGAR
Insider filers
9
Insider buys (7)
$63.4M
Insider sells (41)
$190.5M
Insider sentiment
Net sellingNet insider flow of $127.1M in net selling since February 2025, and $184.0M in net selling over the last 12 months.
Recent SION insider transactions
| Date | Insider | Role | Type | Shares | Price | Value | Filing |
|---|---|---|---|---|---|---|---|
| Sep 21, 2026 | Peter Kolchinsky | Director, 10% Owner | Sale | 3.4M | $6.33 | $21.8M | SEC ↗ |
| Jul 9, 2026 | Peter A. Thompson | Director | Sale | 85.9K | $44.86 | $3.9M | SEC ↗ |
| Jul 9, 2026 | ORBIMED ADVISORS LLC | Director | Sale | 85.9K | $44.86 | $3.9M | SEC ↗ |
| Jul 7, 2026 | Jennifer Fitzpatrick | Chief Legal Officer | Sale | 10.3K | $43.60 | $446.9K | SEC ↗ |
| Jul 2, 2026 | Peter A. Thompson | Director | Sale | 115.8K | $45.50 | $5.3M | SEC ↗ |
| Jul 2, 2026 | ORBIMED ADVISORS LLC | Director | Sale | 115.8K | $45.50 | $5.3M | SEC ↗ |
| May 30, 2026 | Peter A. Thompson | Director | Sale | 101 | $44.49 | $4.5K | SEC ↗ |
| May 30, 2026 | ORBIMED ADVISORS LLC | Director | Sale | 101 | $44.49 | $4.5K | SEC ↗ |
| May 11, 2026 | Peter A. Thompson | Director | Sale | 293.0K | $45.62 | $13.4M | SEC ↗ |
| May 11, 2026 | ORBIMED ADVISORS LLC | Director | Sale | 293.0K | $45.62 | $13.4M | SEC ↗ |
| Apr 22, 2026 | Peter A. Thompson | Director | Sale | 55.3K | $44.67 | $2.5M | SEC ↗ |
| Apr 22, 2026 | ORBIMED ADVISORS LLC | Director | Sale | 55.3K | $44.67 | $2.5M | SEC ↗ |
| Apr 16, 2026 | Peter A. Thompson | Director | Sale | 510.6K | $44.94 | $22.9M | SEC ↗ |
| Apr 16, 2026 | ORBIMED ADVISORS LLC | Director | Sale | 510.6K | $44.94 | $22.9M | SEC ↗ |
| Mar 6, 2026 | Jennifer Fitzpatrick | Chief Legal Officer | Sale | 10.3K | $33.86 | $347.0K | SEC ↗ |
| Feb 5, 2026 | Peter A. Thompson | Director | Sale | 31.0K | $44.58 | $1.4M | SEC ↗ |
| Feb 5, 2026 | ORBIMED ADVISORS LLC | Director | Sale | 31.0K | $44.58 | $1.4M | SEC ↗ |
| Jan 26, 2026 | TPG GP A, LLC | 10% Owner | Sale | 250.0K | $40.00 | $10.0M | SEC ↗ |
| Dec 30, 2025 | ORBIMED ADVISORS LLC | Director | Sale | 33.4K | $44.55 | $1.5M | SEC ↗ |
| Dec 30, 2025 | Peter A. Thompson | Director | Sale | 33.4K | $44.55 | $1.5M | SEC ↗ |
| Dec 20, 2025 | ORBIMED ADVISORS LLC | Director | Sale | 1.9K | $44.49 | $83.4K | SEC ↗ |
| Dec 20, 2025 | Peter A. Thompson | Director | Sale | 1.9K | $44.49 | $83.4K | SEC ↗ |
| Dec 9, 2025 | Jennifer Fitzpatrick | Chief Legal Officer | Sale | 10.3K | $40.52 | $415.3K | SEC ↗ |
| Nov 26, 2025 | ORBIMED ADVISORS LLC | Director | Sale | 108.1K | $44.55 | $4.8M | SEC ↗ |
| Nov 26, 2025 | Peter A. Thompson | Director | Sale | 108.1K | $44.55 | $4.8M | SEC ↗ |
Showing the 25 most recent of 48 Form 4 filings for Sionna Therapeutics, Inc..
Most active SION insiders
- ORBIMED ADVISORS LLC11 filings
- Peter A. Thompson11 filings
- Bruce Booth5 filings
- Michael Cloonan5 filings
- Peter Kolchinsky5 filings
Ask anything about SION insider activity
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Open the AI agentSION insider trading FAQ
Are Sionna Therapeutics, Inc. insiders buying or selling?
In the last 12 months, Sionna Therapeutics, Inc. insiders reported 0 open-market purchases ($0) and 33 sales ($184.0M) — net selling of $184.0M. Since February 2025, Trabud has recorded 48 Form 4 filings for SION: 7 buys ($63.4M) and 41 sells ($190.5M). Over the full record that is net selling of $127.1M.
How many insiders trade SION stock?
9 distinct insider filers — officers, directors, 10%+ owners, and investment groups filing jointly — have reported Form 4 transactions for Sionna Therapeutics, Inc.. The most recent filing was accepted on Sep 21, 2026.
Where does Trabud get SION insider trading data?
All SION insider trading data comes directly from official SEC EDGAR Form 4 filings, which corporate insiders must submit within two business days of a transaction under Section 16(a) of the Securities Exchange Act of 1934.