SEPNHealthcareSmall-Cap

Septerna, Inc. Insider Trading Activity

Every SEC Form 4 insider transaction reported for Septerna, Inc. (SEPN), sourced directly from SEC EDGAR and updated as new filings are accepted.

Last updated:

Quick Answer

Are SEPN insiders buying or selling?

Septerna, Inc. insiders reported 10 open-market buys ($101.4M) and 15 sells ($68.7M) across 25 Form 4 filings — a net buying position of $32.7M.

Source: SEC EDGAR Form 4

Key Statistics (as of Sep 3, 2026)

Total Form 4 filings
25
SEC EDGAR
Insider filers
9
Insider buys (10)
$101.4M
Insider sells (15)
$68.7M

Insider sentiment

Net buying

Net insider flow of $32.7M in net buying. 1 insider buy in the last 90 days.

Recent SEPN insider transactions

DateInsiderRoleTypeSharesPriceValue
Sep 3, 2026Daniel D. LongSVP, Drug DiscoverySale3.3K$37.83$126.1K
Aug 14, 2026Third Rock Ventures V, L.P.10% OwnerPurchase147.2K$50.27$7.4M
Aug 14, 2026Peter KolchinskyDirector, 10% OwnerSale1.5M$42.50$63.5M
Aug 13, 2026Elizabeth BhattPresident and COOSale25.0K$44.00$1.1M
Aug 5, 2026Daniel D. LongSVP, Drug DiscoverySale3.3K$34.47$114.9K
Jul 17, 2026Elizabeth BhattPresident and COOSale4.0K$33.99$136.0K
Jul 2, 2026Daniel D. LongSVP, Drug DiscoverySale3.3K$34.36$114.5K
Jun 30, 2026Samira ShaikhlyChief People OfficerSale2.2K$35.18$76.6K
Jun 24, 2026Daniel D. LongSVP, Drug DiscoverySale15.0K$35.51$532.6K
Jun 17, 2026Samira ShaikhlyChief People OfficerSale6.3K$35.08$219.2K
Jun 3, 2026Samira ShaikhlyChief People OfficerSale5.9K$28.93$171.7K
May 28, 2026Samira ShaikhlyChief People OfficerSale11.8K$30.06$354.7K
Apr 17, 2026Elizabeth BhattPresident and COOSale4.0K$24.34$97.3K
Mar 5, 2026Samira ShaikhlyChief People OfficerSale70.5K$28.10$2.0M
Feb 20, 2026Elizabeth BhattPresident and COOSale4.0K$28.97$115.9K
Nov 14, 2025Daniel D. LongSVP, Drug DiscoverySale3.5K$18.06$63.2K
Mar 10, 2025Alan EzekowitzDirectorPurchase13.3K$6.93$92.3K
Mar 7, 2025Alan EzekowitzDirectorPurchase86.7K$5.95$515.9K
Feb 27, 2025Jeffrey FinerCEO and PresidentPurchase17.0K$5.70$97.0K
Feb 27, 2025Gil M LabrucherieChief Financial OfficerPurchase10.0K$5.69$56.9K
Feb 26, 2025Third Rock Ventures VI, L.P.10% OwnerPurchase18.9K$6.00$113.1K
Feb 24, 2025Third Rock Ventures VI, L.P.10% OwnerPurchase1.0M$5.93$6.2M
Feb 21, 2025Gil M LabrucherieChief Financial OfficerPurchase30.0K$5.74$172.3K
Oct 30, 2024Peter KolchinskyDirector, 10% OwnerPurchase4.2M$18.00$75.1M
Oct 28, 2024Third Rock Ventures V, L.P.10% OwnerPurchase650.0K$18.00$11.7M

Showing the 25 most recent of 25 Form 4 filings for Septerna, Inc..

Most active SEPN insiders

  • Daniel D. Long5 filings
  • Samira Shaikhly5 filings
  • Elizabeth Bhatt4 filings
  • Alan Ezekowitz2 filings
  • Gil M Labrucherie2 filings

Ask anything about SEPN insider activity

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SEPN insider trading FAQ

Are Septerna, Inc. insiders buying or selling?

Across 25 SEC Form 4 filings, Septerna, Inc. (SEPN) insiders reported 10 open-market purchases totaling $101.4M and 15 sales totaling $68.7M. That is a net buying position of $32.7M.

How many insiders trade SEPN stock?

9 distinct insider filers — officers, directors, 10%+ owners, and investment groups filing jointly — have reported Form 4 transactions for Septerna, Inc.. The most recent filing was accepted on Sep 3, 2026.

Where does Trabud get SEPN insider trading data?

All SEPN insider trading data comes directly from official SEC EDGAR Form 4 filings, which corporate insiders must submit within two business days of a transaction under Section 16(a) of the Securities Exchange Act of 1934.

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