Septerna, Inc. Insider Trading Activity
Every SEC Form 4 insider transaction reported for Septerna, Inc. (SEPN), sourced directly from SEC EDGAR and updated as new filings are accepted.
By Trabud · Insider-trading data from SEC EDGAR
Latest filing:
Compiled automatically from SEC EDGAR Form 4 filings and refreshed daily. Figures count purchases (code P) and sales (code S) only — not grants, option exercises, or gifts. How this page is built. Not investment advice.
Quick Answer
Are SEPN insiders buying or selling?
In the last 12 months, Septerna, Inc. insiders reported 1 open-market purchase ($7.4M) and 15 sales ($68.7M) — net selling of $61.3M. Since October 2024, Trabud has recorded 25 Form 4 filings for SEPN: 10 buys ($101.4M) and 15 sells ($68.7M).
Source: SEC EDGAR Form 4
What stands out
- The largest open-market purchase in the last 12 months was $7.4M by Third Rock Ventures V, L.P. (10% Owner) on Aug 14, 2026. SEC ↗
- The most recent open-market purchase was reported on Aug 14, 2026 (2 months ago).
Key Statistics (October 2024 – Sep 3, 2026)
Total Form 4 filings
25
SEC EDGAR
Insider filers
9
Insider buys (10)
$101.4M
Insider sells (15)
$68.7M
Insider sentiment
Net buyingNet insider flow of $32.7M in net buying since October 2024, and $61.3M in net selling over the last 12 months. 1 insider buy in the last 90 days.
Recent SEPN insider transactions
| Date | Insider | Role | Type | Shares | Price | Value | Filing |
|---|---|---|---|---|---|---|---|
| Sep 3, 2026 | Daniel D. Long | SVP, Drug Discovery | Sale | 3.3K | $37.83 | $126.1K | SEC ↗ |
| Aug 14, 2026 | Third Rock Ventures V, L.P. | 10% Owner | Purchase | 147.2K | $50.27 | $7.4M | SEC ↗ |
| Aug 14, 2026 | Peter Kolchinsky | Director, 10% Owner | Sale | 1.5M | $42.50 | $63.5M | SEC ↗ |
| Aug 13, 2026 | Elizabeth Bhatt | President and COO | Sale | 25.0K | $44.00 | $1.1M | SEC ↗ |
| Aug 5, 2026 | Daniel D. Long | SVP, Drug Discovery | Sale | 3.3K | $34.47 | $114.9K | SEC ↗ |
| Jul 17, 2026 | Elizabeth Bhatt | President and COO | Sale | 4.0K | $33.99 | $136.0K | SEC ↗ |
| Jul 2, 2026 | Daniel D. Long | SVP, Drug Discovery | Sale | 3.3K | $34.36 | $114.5K | SEC ↗ |
| Jun 30, 2026 | Samira Shaikhly | Chief People Officer | Sale | 2.2K | $35.18 | $76.6K | SEC ↗ |
| Jun 24, 2026 | Daniel D. Long | SVP, Drug Discovery | Sale | 15.0K | $35.51 | $532.6K | SEC ↗ |
| Jun 17, 2026 | Samira Shaikhly | Chief People Officer | Sale | 6.3K | $35.08 | $219.2K | SEC ↗ |
| Jun 3, 2026 | Samira Shaikhly | Chief People Officer | Sale | 5.9K | $28.93 | $171.7K | SEC ↗ |
| May 28, 2026 | Samira Shaikhly | Chief People Officer | Sale | 11.8K | $30.06 | $354.7K | SEC ↗ |
| Apr 17, 2026 | Elizabeth Bhatt | President and COO | Sale | 4.0K | $24.34 | $97.3K | SEC ↗ |
| Mar 5, 2026 | Samira Shaikhly | Chief People Officer | Sale | 70.5K | $28.10 | $2.0M | SEC ↗ |
| Feb 20, 2026 | Elizabeth Bhatt | President and COO | Sale | 4.0K | $28.97 | $115.9K | SEC ↗ |
| Nov 14, 2025 | Daniel D. Long | SVP, Drug Discovery | Sale | 3.5K | $18.06 | $63.2K | SEC ↗ |
| Mar 10, 2025 | Alan Ezekowitz | Director | Purchase | 13.3K | $6.93 | $92.3K | SEC ↗ |
| Mar 7, 2025 | Alan Ezekowitz | Director | Purchase | 86.7K | $5.95 | $515.9K | SEC ↗ |
| Feb 27, 2025 | Jeffrey Finer | CEO and President | Purchase | 17.0K | $5.70 | $97.0K | SEC ↗ |
| Feb 27, 2025 | Gil M Labrucherie | Chief Financial Officer | Purchase | 10.0K | $5.69 | $56.9K | SEC ↗ |
| Feb 26, 2025 | Third Rock Ventures VI, L.P. | 10% Owner | Purchase | 18.9K | $6.00 | $113.1K | SEC ↗ |
| Feb 24, 2025 | Third Rock Ventures VI, L.P. | 10% Owner | Purchase | 1.0M | $5.93 | $6.2M | SEC ↗ |
| Feb 21, 2025 | Gil M Labrucherie | Chief Financial Officer | Purchase | 30.0K | $5.74 | $172.3K | SEC ↗ |
| Oct 30, 2024 | Peter Kolchinsky | Director, 10% Owner | Purchase | 4.2M | $18.00 | $75.1M | SEC ↗ |
| Oct 28, 2024 | Third Rock Ventures V, L.P. | 10% Owner | Purchase | 650.0K | $18.00 | $11.7M | SEC ↗ |
Showing the 25 most recent of 25 Form 4 filings for Septerna, Inc..
Most active SEPN insiders
- Daniel D. Long5 filings
- Samira Shaikhly5 filings
- Elizabeth Bhatt4 filings
- Alan Ezekowitz2 filings
- Gil M Labrucherie2 filings
Ask anything about SEPN insider activity
Use Trabud's AI agent to query Septerna, Inc.'s Form 4 history in plain English — "Show me SEPN CEO purchases this year" or compare it against any other ticker.
Open the AI agentSEPN insider trading FAQ
Are Septerna, Inc. insiders buying or selling?
In the last 12 months, Septerna, Inc. insiders reported 1 open-market purchase ($7.4M) and 15 sales ($68.7M) — net selling of $61.3M. Since October 2024, Trabud has recorded 25 Form 4 filings for SEPN: 10 buys ($101.4M) and 15 sells ($68.7M). Over the full record that is net buying of $32.7M.
How many insiders trade SEPN stock?
9 distinct insider filers — officers, directors, 10%+ owners, and investment groups filing jointly — have reported Form 4 transactions for Septerna, Inc.. The most recent filing was accepted on Sep 3, 2026.
Where does Trabud get SEPN insider trading data?
All SEPN insider trading data comes directly from official SEC EDGAR Form 4 filings, which corporate insiders must submit within two business days of a transaction under Section 16(a) of the Securities Exchange Act of 1934.