OPKO HEALTH, INC. Insider Trading Activity
Every SEC Form 4 insider transaction reported for OPKO HEALTH, INC. (OPK), sourced directly from SEC EDGAR and updated as new filings are accepted.
By Trabud · Insider-trading data from SEC EDGAR
Latest filing:
Compiled automatically from SEC EDGAR Form 4 filings and refreshed daily. Figures count purchases (code P) and sales (code S) only — not grants, option exercises, or gifts. How this page is built. Not investment advice.
Quick Answer
Are OPK insiders buying or selling?
In the last 12 months, OPKO HEALTH, INC. insiders reported 6 open-market purchases ($3.2M) and 0 sales ($0) — net buying of $3.2M. Since January 2018, Trabud has recorded 331 Form 4 filings for OPK: 331 buys ($95.2M) and 0 sells ($0).
Source: SEC EDGAR Form 4
What stands out
- The largest open-market purchase in the last 12 months was $771.3K by Phillip Frost MD ET AL (CEO & Chairman) on Nov 20, 2025. SEC ↗
- The most recent open-market purchase was reported on Mar 20, 2026 (6 months ago).
Key Statistics (January 2018 – Mar 20, 2026)
Total Form 4 filings
331
SEC EDGAR
Insider filers
12
Insider buys (331)
$95.2M
Insider sells (0)
$0
Insider sentiment
Net buyingNet insider flow of $95.2M in net buying since January 2018, and $3.2M in net buying over the last 12 months.
Recent OPK insider transactions
| Date | Insider | Role | Type | Shares | Price | Value | Filing |
|---|---|---|---|---|---|---|---|
| Mar 20, 2026 | John A Paganelli | Director | Purchase | 10.0K | $1.14 | $11.3K | SEC ↗ |
| Nov 21, 2025 | Phillip Frost MD ET AL | CEO & Chairman | Purchase | 580.0K | $1.33 | $768.8K | SEC ↗ |
| Nov 20, 2025 | Phillip Frost MD ET AL | CEO & Chairman | Purchase | 580.0K | $1.33 | $771.3K | SEC ↗ |
| Nov 19, 2025 | Phillip Frost MD ET AL | CEO & Chairman | Purchase | 580.0K | $1.31 | $759.1K | SEC ↗ |
| Nov 18, 2025 | Phillip Frost MD ET AL | CEO & Chairman | Purchase | 533.3K | $1.27 | $678.9K | SEC ↗ |
| Oct 31, 2025 | Phillip Frost MD ET AL | CEO & Chairman | Purchase | 150.0K | $1.42 | $213.4K | SEC ↗ |
| Aug 8, 2025 | Phillip Frost MD ET AL | CEO & Chairman | Purchase | 675.0K | $1.32 | $891.0K | SEC ↗ |
| Apr 10, 2025 | Phillip Frost MD ET AL | CEO & Chairman | Purchase | 125.0K | $1.36 | $169.7K | SEC ↗ |
| Apr 8, 2025 | Phillip Frost MD ET AL | CEO & Chairman | Purchase | 125.0K | $1.48 | $184.7K | SEC ↗ |
| Apr 1, 2025 | Phillip Frost MD ET AL | CEO & Chairman | Purchase | 100.0K | $1.65 | $164.8K | SEC ↗ |
| Mar 28, 2025 | Phillip Frost MD ET AL | CEO & Chairman | Purchase | 150.0K | $1.70 | $254.4K | SEC ↗ |
| Mar 17, 2025 | Phillip Frost MD ET AL | CEO & Chairman | Purchase | 200.0K | $1.74 | $347.8K | SEC ↗ |
| Mar 1, 2025 | Phillip Frost MD ET AL | CEO & Chairman | Purchase | 67.4K | $1.71 | $115.3K | SEC ↗ |
| Jan 28, 2025 | Phillip Frost MD ET AL | CEO & Chairman | Purchase | 47.5K | $1.47 | $70.1K | SEC ↗ |
| Jan 17, 2025 | Phillip Frost MD ET AL | CEO & Chairman | Purchase | 150.0K | $1.47 | $220.4K | SEC ↗ |
| Jan 15, 2025 | Phillip Frost MD ET AL | CEO & Chairman | Purchase | 500.0K | $1.48 | $740.9K | SEC ↗ |
| Dec 13, 2024 | Phillip Frost MD ET AL | CEO & Chairman | Purchase | 125.0K | $1.60 | $199.4K | SEC ↗ |
| Dec 11, 2024 | Phillip Frost MD ET AL | CEO & Chairman | Purchase | 500.0K | $1.56 | $781.0K | SEC ↗ |
| Nov 29, 2024 | Phillip Frost MD ET AL | CEO & Chairman | Purchase | 199.1K | $1.53 | $305.4K | SEC ↗ |
| Nov 22, 2024 | Phillip Frost MD ET AL | CEO & Chairman | Purchase | 100.0K | $1.59 | $159.0K | SEC ↗ |
| Nov 21, 2024 | Phillip Frost MD ET AL | CEO & Chairman | Purchase | 280.2K | $1.50 | $421.5K | SEC ↗ |
| Nov 14, 2024 | Phillip Frost MD ET AL | CEO & Chairman | Purchase | 100.0K | $1.62 | $162.0K | SEC ↗ |
| Nov 8, 2024 | Phillip Frost MD ET AL | CEO & Chairman | Purchase | 280.2K | $1.50 | $421.5K | SEC ↗ |
| May 24, 2024 | Phillip Frost MD ET AL | CEO & Chairman | Purchase | 100.0K | $1.27 | $126.9K | SEC ↗ |
| May 17, 2024 | Phillip Frost MD ET AL | CEO & Chairman | Purchase | 164.0K | $1.29 | $211.2K | SEC ↗ |
Showing the 25 most recent of 331 Form 4 filings for OPKO HEALTH, INC..
Most active OPK insiders
- Phillip Frost MD ET AL285 filings
- Robert Scott Fishel10 filings
- Jane PH D Hsiao9 filings
- Steven D Rubin7 filings
- Richard C Pfenniger JR5 filings
Ask anything about OPK insider activity
Use Trabud's AI agent to query OPKO HEALTH, INC.'s Form 4 history in plain English — "Show me OPK CEO purchases this year" or compare it against any other ticker.
Open the AI agentOPK insider trading FAQ
Are OPKO HEALTH, INC. insiders buying or selling?
In the last 12 months, OPKO HEALTH, INC. insiders reported 6 open-market purchases ($3.2M) and 0 sales ($0) — net buying of $3.2M. Since January 2018, Trabud has recorded 331 Form 4 filings for OPK: 331 buys ($95.2M) and 0 sells ($0). Over the full record that is net buying of $95.2M.
How many insiders trade OPK stock?
12 distinct insider filers — officers, directors, 10%+ owners, and investment groups filing jointly — have reported Form 4 transactions for OPKO HEALTH, INC.. The most recent filing was accepted on Mar 20, 2026.
Where does Trabud get OPK insider trading data?
All OPK insider trading data comes directly from official SEC EDGAR Form 4 filings, which corporate insiders must submit within two business days of a transaction under Section 16(a) of the Securities Exchange Act of 1934.