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Opaleye Management Inc. Insider Trading Activity

Every SEC Form 4 transaction reported by Opaleye Management Inc., sourced directly from SEC EDGAR and updated as new filings are accepted.

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Quick Answer

Is Opaleye Management Inc. buying or selling?

Opaleye Management Inc. reported 156 open-market buys ($62.8M) and 40 sells ($27.6M) across 196 Form 4 filings at 10 companies — a net buying position of $35.2M.

Source: SEC EDGAR Form 4

Key Statistics (as of Jul 16, 2026)

Total Form 4 filings
196
SEC EDGAR
Companies
10
Buys (156)
$62.8M
Sells (40)
$27.6M

Insider sentiment

Net buying

Net insider flow of $35.2M in net buying, filed between Jan 2, 2020 – Jul 16, 2026.

Companies Opaleye Management Inc. files for

#CompanyForm 4 filings
1TCONTracon Pharmaceuticals, Inc.35
2HROWHARROW, INC.32
3CDXSCODEXIS, INC.26
4TARAProtara Therapeutics, Inc.24
5SLGLSol-Gel Technologies Ltd.19
6TELATELA Bio, Inc.18
7ACOGAlpha Cognition Inc.17
8ETONEton Pharmaceuticals, Inc.16
9SNWVSANUWAVE Health, Inc.6
10OCULOCULAR THERAPEUTIX, INC2

Recent Opaleye Management Inc. transactions

DateTickerRoleTypeSharesValue
Jul 16, 2026ETON10% OwnerSale28.3K$1.1M
Jul 15, 2026SLGL10% OwnerPurchase1.7K$124.8K
Jul 7, 2026ETON10% OwnerSale126.7K$4.8M
Jul 2, 2026SLGL10% OwnerPurchase1.7K$123.2K
Jun 29, 2026ACOG10% OwnerPurchase152.5K$976.5K
Jun 16, 2026ACOG10% OwnerPurchase7.7K$45.8K
Jun 11, 2026ACOG10% OwnerPurchase30.7K$183.7K
Jun 9, 2026ACOG10% OwnerPurchase10.1K$58.6K
May 29, 2026ACOG10% OwnerPurchase73.7K$434.7K
May 22, 2026ACOG10% OwnerPurchase24.4K$140.5K
May 22, 2026SLGL10% OwnerPurchase1.6K$100.7K
May 19, 2026ACOG10% OwnerPurchase34.0K$196.0K
May 14, 2026SLGL10% OwnerPurchase3.4K$231.5K
May 4, 2026SNWV10% OwnerSale35.6K$574.2K
Apr 30, 2026SNWV10% OwnerSale70.6K$1.3M
Apr 21, 2026SNWV10% OwnerSale16.5K$337.0K
Mar 31, 2026ACOG10% OwnerPurchase11.8K$60.0K
Mar 26, 2026ACOG10% OwnerPurchase20.1K$108.6K
Mar 24, 2026SLGL10% OwnerPurchase39.7K$2.9M
Mar 20, 2026ACOG10% OwnerPurchase4.6K$26.2K
Mar 18, 2026ACOG10% OwnerPurchase1.3K$7.7K
Mar 13, 2026ACOG10% OwnerPurchase13.1K$75.7K
Mar 10, 2026ACOG10% OwnerPurchase4.1K$23.8K
Mar 6, 2026ACOG10% OwnerPurchase66.8K$387.6K
Mar 4, 2026ACOG10% OwnerPurchase71.4K$411.6K

Showing the 25 most recent filings of 196. Screen every filing.

Opaleye Management Inc. insider trading FAQ

Is Opaleye Management Inc. buying or selling?

Across 196 SEC Form 4 filings, Opaleye Management Inc. reported 156 open-market purchases totaling $62.8M and 40 sales totaling $27.6M — a net buying position of $35.2M.

Which companies does Opaleye Management Inc. file Form 4s for?

Opaleye Management Inc. has reported insider transactions at 10 companies, most often Tracon Pharmaceuticals, Inc. (TCON), HARROW, INC. (HROW), CODEXIS, INC. (CDXS), Protara Therapeutics, Inc. (TARA), Sol-Gel Technologies Ltd. (SLGL).

How far back does Opaleye Management Inc.'s filing history go?

Trabud holds Opaleye Management Inc.'s SEC Form 4 filings from Jan 2, 2020 – Jul 16, 2026, sourced directly from SEC EDGAR.

Where does Trabud get Opaleye Management Inc.'s insider trading data?

Directly from SEC EDGAR Form 4 filings. Every transaction on this page is a real filing accepted by the SEC, updated as new filings arrive.

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